MSC interactions with cytoskeletal elements, mobile−mobile contacts, extracellular matrix and topography might have profound consequences on multipotential MSCs. a Harvesting MSCs from the bone marrow niche with its condensed cell-loaded setting and culturing them in vitro eliminates the mobile−cell cadherin and connexin connections and replace
JXL and JFG carried out and wrote the manuscript; JXL, FPW and QN collected the references and made the table; JXL drew the figures; ZXL and CG modified the manuscript and LYZ built the manuscript and accredited the ultimate manuscript for publication. All authors read and accredited the ultimate manuscript. The decisive roles of chemokines and re
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